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Anatomy by Bhushan, Vikas

By Bhushan, Vikas

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Fig. 4. Note extensive and severe pyoderma in patient with Chédiak-Higashi syndrome. Disorders with Oral or Perioral Soft Tissue Involvement 49 Differential Diagnosis. The differential diagnosis should include tyrosinase-positive albinism, Hermansky-Pudlak syndrome, yellow mutant albinism, cyclic neutropenia, and agranulocytosis of various etiologies. been found in normal relatives of patients with the Chédiak-Higashi syndrome. Laboratory Aids. Demonstration of large eosinophilic peroxidase-positive inclusion bodies in myeloblasts and promyelocytes along with an existing neutropenia is of great value in establishing a diagnosis.

Fig. 27. Note characteristic absence of knuckles in a patient with PHP. Disorders with Dental Involvement 41 Laboratory Aids. Hypocalcemia, hyperphosphatemia, diminished renal excretion of phosphate, and lack of renal response to exogenous administration of parathormone characterize this disorder. Synonym. Albright hereditary osteodystrophy. " Report of three cases. Endocrinology 30:922-932, 1942. Aurback GD, et al: Polypeptide hormones and calcium metabolism. Ann Intern Med 70:1243-1265, 1969.

15. Mouth presents a characteristic horizontal slit-like appearance.

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